31例儿童视神经炎的临床特点和转归分析Clinical Characteristics and Outcome Analysis of 31 Cases of Children Optic Neuritis
余姗姗;吴茜;陈博;卜碧涛;
摘要(Abstract):
目的:总结儿童视神经炎(ON)的临床特点和预后。方法:回顾性分析2007年1月至2013年1月我院确诊为ON的患儿共31例(52眼)的临床资料及随访结果,比较不同临床特征对ON转化为多发性硬化(MS)或视神经脊髓炎(NMO)的影响。结果:10例(32.3%)病前1~3周有上呼吸道感染史,21例(67.7%)双眼起病,初诊视力下降至≤0.1共29眼(55.8%),13例(41.9%)出现视乳头炎;治疗后视力恢复至≥1.0者共21眼(40.4%)。平均随访时间为43.6月(12~84月),9例(29.0%)在随访期间转化为MS或NMO,其中6例诊断为MS,3例诊断为NMO。2组复发比例差异有统计学意义(P=0.015)。结论:儿童ON双眼起病多见,视力下降严重,治疗后恢复良好。
关键词(KeyWords): 视神经炎;多发性硬化;视神经脊髓炎;临床转归;儿童
基金项目(Foundation):
作者(Author): 余姗姗;吴茜;陈博;卜碧涛;
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参考文献(References):
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