蒯建科;于代华;高昌俊;王彬荣;孙绪德;

• 1:第四军医大学唐都医院麻醉科

摘要(Abstract)：

目的:探讨盐酸右美托咪定用于立体定向颅内血肿微创抽吸术治疗脑出血的麻醉效果。方法:高血压脑出血患者69例,随机分为观察组34例及对照组35例。2组术前麻醉时均先静脉注射芬太尼1μg/kg,对照组采用常规麻醉方法,观察组采用盐酸右美托咪定进行麻醉,记录患者进入手术室(T1)、应用丙泊酚或盐酸右美托咪定后(T2)、安置头架后(T3)、钻孔时(T4)时的平均动脉压(MAP)、氧分压(PaO2)、二氧化碳分压(PaCO2),并比较2组出现的不良反应。结果:与对照组比较,观察组心率在T3、T4时间明显降低,PaO2明显升高,差异有统计学意义(P<0.05),MAP、PaCO2在T4时间差异有统计学意义(P<0.05)。观察组术中低血压、心动过速、躁动及术后呕吐发生人数低于对照组,差异有统计学意义(P<0.05)。结论:盐酸右美托咪定用于立体定向颅内血肿微创抽吸术治疗脑出血的麻醉效果较丙泊酚好良好,心率、MAP、PaO2波动小,呼吸抑制较少。

关键词(KeyWords)： 盐酸右美托咪定;颅内血肿微创抽吸术;麻醉效果

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 蒯建科;于代华;高昌俊;王彬荣;孙绪德;

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参考文献(References)：

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