震颤分析及其相关疾病的真实世界研究Real-World Studies of Tremor Analysis and Its Related Diseases
韩燕飞,李伟敏,许春伶
摘要(Abstract):
目的:通过分析震颤患者的临床资料、震颤分析结果及最终诊断,以期明确震颤分析检查的意义并为临床医生提供帮助。方法:按入排标准筛选2022年1月~2024年1月在北京友谊医院神经内科肌电图室进行震颤分析检查的患者,总结入组患者的临床资料及震颤分析结果,对原发性震颤和帕金森病2组患者的临床资料和震颤分析结果进行对比,对其他震颤患者的临床资料和震颤分析结果进行总结。结果:本研究共入组患者192例,其中原发性震颤103例(53.6%),帕金森病74例(38.5%),肌张力障碍4例(2.1%),周围神经病后震颤3例(1.6%),直立性震颤3例(1.6%),增强的生理性震颤4例(2.1%)和多系统萎缩1例(0.5%)。比较原发性震颤和帕金森病患者,结果显示2组患者的年龄、病程、是否存在家族史、起病部位、震颤方式、收缩形式以及是否存在谐波等方面差异均存在统计学意义(P<0.05);2组在静止、姿势、意向、持物1 kg情况下,震颤频率差异均存在统计学意义(P<0.05),而震颤波幅差异均无统计学意义(P>0.05)。结论:本研究通过对震颤分析检查进行真实世界的研究,发现表现为震颤的疾病复杂多样,震颤分析是有效的检查手段,特别是在原发性震颤和帕金森病的鉴别方面,有着重要价值。
关键词(KeyWords): 震颤分析;原发性震颤;帕金森病
基金项目(Foundation):
作者(Author): 韩燕飞,李伟敏,许春伶
DOI: 10.16780/j.cnki.sjssgncj.20240418
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